Friday, May 27th, 2022, 15:00-16:00
PSP.01: A. Guni
Phytochemical screening on biological study on the plant Linum usitatissimum Linn.
PSP.02: O. Wronikowska-Denysiuk, A. Michalak, T. Słowik, B. Budzyńska
The role of oxytocin in mephedrone-induced social reward
PSP.03: A. Stasiulewicz, J. Sulkowska
Identification of Novel Ligands of Cannabinoid Receptor 2: In Silico Screening Assay and In Vitro Evaluation
PSP.04: S. Janowska, D. Khylyuk, A. Bielawska, A. Szymanowska, K. Bielawski, M. Wujec
Synthesis and anticancer evaluation of new 1,3,4-thiadiazole derivatives
PSP.05: I. Kwiatkowska, J. Hermanowicz, R. Czarnomysy, A. Bielawska, M. Mojzych, K. Bielawski, D. Pawlak
Proapoptotic activity of MM-129 in experimental colon cancer models
PSP.06: R. Mallea
Analysis on the use of personalized medicines produced via 2D and 3D printers
PSP.07: M. Ahmed
Curcumin derivatives: Anti-inflammatory, analgesic, ulcerogenic, cyclooxygenase-2 inhibition and molecular docking studies
PSP.08: E. Ozimina-Kamińska, A. Minecka, B. Hachuła, K. Jurkiewicz, K. Kamiński, B. Milanowski
The impact of vitrification method on the physico-chemical properties and dissolution rate of bosentan
PSP.09: M. Rybicki, A. Klimek-Turek, T. Dzido
Solvent Front Position Extraction as a powerful sample preparation procedure for the quantitation of coccidiostats
PSP.10: A. Mazurek, T. Simonson
Parametrization of the AMOEBA polarizable force field for 17-β-estradiol and cyclodextrin basic unit. Step into the Free Energy Perturbation calculations and Endocrine Disrupting Chemicals analysis.
PSP.11: F. Menezes, G. Popowicz
Quantum Chemistry in a Pocket
PSP.12: A. Laskowska, A. Wilczak, W. Skowrońska, P. Michel, M. F. Melzig, M. E. Czerwińska
Fruits of Hippophaë rhamnoides – a question about their preventive role in gut barrier leakage, epithelial inflammation, and glucose transport
PSP.13: D. Dziubak, K. Burdach, S. Sęk
Could Oligourea Foldamers Become New Antibiotics?
PSP.14: K. Burdach, J. Juhaniewicz-Dębińska, S. Sęk
The new field of research in drug development – lipooligoureas based on peptidomimetic foldamers
PSP.15: A. Witkowska, E. U. Stolarczyk, J. Giebułtowicz
Development of a sensitive screening method for simultaneous determination of nine genotoxic nitrosamines in active pharmaceutical ingredients by GC-MS
PSP.16: M. Zaborowska, D. Matyszewska, R. Bilewicz
Changes in surface properties of lipid raft models exposed to cholesterol-lowering drugs
Friday, May 27th, 2022, 16:00-17:00
PPP.001: A. Patyra, I. Herczyńska, A. Kiss
Stilbenes in wood industry waste materials – study on composition of conifers branch wood
PPP.002: P. Kozyra, K. Mańko, A. Serefko, A. Szopa, E. Poleszak, M. Pitucha
Effect of selected derivatives of 4-nitrophanoxyacetic acid hydrazide on the early development stages of Danio rerio
PPP.003: J. Hermanowicz, I. Kwiatkowska, A. Surażyński, D. Pawlak
MM-129 as novel potential anticancer agent against colorectal cancer
PPP.004: S. Michałek, M. Stypik, M. Zagozda, N. Orłowska, M. Banach, U. Kędzierska, B. M. Zygmunt, K. Gala, M. Dziachan, B. Dymek, D. Zdżalik-Bielecka, P. Gunerka, P. Turowski, Z. Ochal, K. Dubiel, J. Pieczykolan, M. Wieczorek
Indol-4-yl pyrazolo[1,5-a]pyrimidine derivatives: highly active and selective inhibitors of PI3Kδ – potential candidates for treatment of chronic obstructive pulmonary disease and asthma.
PPP.005: M. Stypik, S. Michałek, M. Zagozda, N. Orłowska, M. Banach, U. Kędzierska, B. M. Zygmunt, K. Gala, M. Dziachan, D. Zdżalik-Bielecka, B. Dymek, P. Gunerka, P. Turowski, Z. Ochal, K. Dubiel, J. Pieczykolan, M. Wieczorek
CPL302415 – pyrazolo[1,5-a]pyrimidine derivative as a novel, very active and selective PI3Kδ inhibitor, highly potent drug candidate for SLE and other inflammatory and autoimmune diseases.
PPP.006: A. Surażyński, T. Guszczyn, A. Kazberuk, M. Chalecka
Platelet-rich plasma counteracts interleukin-1 induced inhibition of collagen biosynthesis through recovery of impaired β1-integrin signaling and prolidase activity in human skin fibroblasts
PPP.007: M. Chalecka, A. Kazberuk, A. Surażyński
The role of oxidative stress in prolidase-dependent chemotherapy resistance of breast cancer cells MCF7
PPP.008: R. Czarnomysy, D. Radomska, A. Muszynska, O. Szewczyk, A. Bielawska, K. Bielawski
Bioactive basis of antitumor activity of novel transition metal complexes with berenil and nitroimidazole
PPP.009: M. Pawlicka, A. Filip, P. Głaz, M. Kołodziejczyk
Safety of useing soy isoflavonoid-based products in women during and after breast cancer treatment
PPP.010: D. Drozdowska, D. Maliszewski, A. Wróbel, M. Bogdańska, J. Wiśniewska
New benzamides as candidates for AChE and BACE1 inhibitors
PPP.011: E. Martula, B. Morak-Młodawska, M. Jeleń
Novel derivatives of dipyridothiazines – synthesis and ADME analysis
PPP.012: S. Kulczyk, M. Koszytkowska-Stawińska
Novel Drug Design Framework As a Response to Neglected and Emerging Diseases
PPP.013: A. Kocur, D. Marszałek, T. Pawiński
Validation a new LC-MS/MS method of tacrolimus concentration measurment in the blood samples collected by volumetric-absorptive microsampling
PPP.014: D. Radomska, D. Radomski, R. Czarnomysy, K. Bielawski
Evaluation of the anticancer activity of a novel selenoester in MDA-MB-231 triple-negative breast cancer cells
PPP.015: A. Smolarkiewicz-Wyczachowski, S. Bocian, M. Ziegler-Borowska, D. Chełminiak-Dudkiewicz
New chitosan composites with BODIPY compounds as potential photosensitizing drug form for PDT
PPP.016: O. Shuklinova, B. Wiśniowska, G. Wyszogrodzka-Gaweł, B. Lisowski, S. Polak
Physiologically based pharmacokinetic model for informing ropinirole new formulation development
PPP.017: L. Tomorowicz, J. Sławiński, B. Żołnowska, K. Szafrański, A. Kawiak
Design, synthesis and anticancer activity of novel 2-[4-amino-6-R2-1,3,5-triazin-2-ylmethylthio]-N-(1-substituted-imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide derivatives
PPP.018: K. Paruch, A. Biernasiuk, Ł. Popiołek
Synthesis and antimicrobial activity of new derivatives of 4-tert-butylbenzoic acid hydrazide
PPP.019: A. Olędzka, K. Cichocka, K. Woliński, M. F. Melzig, M. E. Czerwińska
Cornus mas fruit – searching of its role in inflammation-related metabolic disorders and the fate of its metabolites after gastrointestinal transformation in vitro
PPP.020: E. Surmiak, J. Zaber, G. Wojtanowicz, J. Kocik, O. Kruc, D. Muszak, B. Musielak, I. Rodriguez, L. Skalniak, K. Magiera-Mularz, T. Holak, J. Kalinowska-Tłuścik
Solubilizer tag effect on PD-L1/inhibitor binding for m-terphenyl derivatives
PPP.021: J. Witkowski, S. Polak, Z. Rogulski, D. Pawelec
In Vitro/In Vivo translation of synergistic combination of MDM2 and MEK inhibitors in melanoma using PBPK/PD modeling
PPP.022: T. Wichur, J. Godyń, I. Góral, A. Więckowska
Dual GSK-3β and IKK2 kinase inhibitors in the group of 2-(cyclopropanecarboxamido)pyridin-4-yl substituted benzenesulfonamides – a new direction in the search for Alzheimer’s disease therapy
PPP.023: P. Nowak, K. Mylkie, M. Ziegler-Borowska
Synthesis of hydrazide starch for the selective release of anti-cancer drugs
PPP.024: K. Mylkie, P. Nowak, M. Ziegler-Borowska
Immobilization of alpha-1-acid glycoprotein on magnetic nanoparticles functionalized with starch and boronic acids
PPP.025: M. Kołtun-Jasion, A. Wrzesień, A. Patyra, A. Kiss
Impact of lignans on the secretion of heme oxydase and pro-inflammatory cytokines
PPP.026: I. Góral, N. Szałaj, D. Panek, T. Wichur, J. Godyń, A. Więckowska
Structure-activity relationship in a series of glycogen synthase kinase 3β inhibitors based on N-(pyridin-2-yl)carboxamide scaffold
PPP.027: A. Stawarska, M. Czerwonka, M. Jelińska, B. Bobrowska-Korczak
The Influence of Supplementation with Zinc in Micro and Nano Forms on the Metabolism of Fatty Acids in Livers of Rats with Breast Cancer
PPP.028: A. Stawarska, M. Czerwonka, B. Bobrowska-Korczak
Zinc affects cholesterol oxidation products and fatty acids composition in rats’ serum
PPP.029: M. Dawidowski, M. Splandesci
Ugi five-center four component reaction (U-5C-4CR) reaction of aminoaldehydes as a potential source of bioactive peptidomimetics
PPP.030: E. U. Stolarczyk, W. Strzempek, M. Łaszcz, A. Leś, E. Menaszek, K. Stolarczyk
Structure elucidation of new compound Thiogenistein oxidation products – antioxidant chemistry and antitumor activity study.
PPP.031: M. Nowacki, V. Napolitano, P. Mróz, E. Pykacz, M. Popiołek, V. Kalel, R. Erdmann, O. Plettenburg, G. Dubin, G. Popowicz, M. Dawidowski
Dibenzo[b,e]azepines and dibenzo[b,f][1,4]oxazepines as novel PEX14-PEX5 protein-protein interaction (PPI) inhibitors
PPP.032: M. Paczkowska-Walendowska, J. Cielecka-Piontek
Using the Design of experiments (DoE) approach to improve the efficiency of active compounds extraction from Polygoni Cuspidati Rhizoma et Radix
PPP.033: A. Jagielska, A. Mardosz, J. Fąfara, K. Sałaciak, J. Śniecikowska, M. Kołaczkowski, A. Newman-Tancredi, K. Pytka
NLX-101, a biased 5-HT1A receptor agonist, shows antidepressant-like effect in corticosterone-induced model of depression in mice.
PPP.034: S. Abouzahra, A. Jagielska, K. Lustyk, M. Kołaczkowski, A. Newman-Tancredi, K. Pytka
NLX-101 does not negatively affect intermediate-term memory consolidation in mice
PPP.035: M. K. Franczak-Rogowska, K. Stępień, T. Pieńko, M. E. Grudzień, M. D. Grudzień, A. A. Mazurek, A. P. Mazurek
Possibility of using hetero-derivatives of fullerene C60 as carriers of drugs containing benzene, naphthalene or anthracene ring – endohedral complexes @C54Y6 and @C55Y5
PPP.036: J. Stocka, R. Platakyte, J. Macyte, J. Ceponkus, V. Sablinskas, P. Rodziewicz
Kinetics of the conformational changes of the valeric acid in the nitrogen matrix: experiment meets theory at finite temperature
PPP.037: J. Wróbel-Szkolak, A. Cwener, Ł. Komsta
TLC fingerprinting of 70 grass species growing in Poland
PPP.038: M. Kałucka, M. Klimaszewska, M. Król, S. Górska-Jakubowska, A. Roszczyk, B. Kaleta, A. Prus, R. Zagożdżon, J. Turło
Optimization of Se and Zn -enriched mycelium of Lentinula edodes (Berk.) Pegler as a immunostimulatory preparation
PPP.039: H. Kierońska, M. Kretkiewicz, K. Rogut, J. Lipner, S. Pikul, A. Krause
Application of Hot Melt Extrusion technology in the development of innovative formulation containing amorphous form of Active Pharmaceutical Ingredient
PPP.040: E. Gniazdowska, E. Gilant
Stability of aripiprazole in human plasma from healthy volunteers
PPP.041: K. Słoczyńska, K. Piska, D. Żelaszczyk, A. Gunia-Krzyżak, J. Popiół, A. Ładyka, P. Żmudzki, E. Pękala
Microbial biotransformation of lipid-lowering drugs fenofibrate and gemfibrozil by Cunninghamella species
PPP.042: G. Ślifirski, M. Król, F. Herold, J. Turło
Synthesis of novel 4-aryl-pyrido[1,2-c]pyrimidine chiral derivatives as potential 5-HT1A/5-HTT ligands
PPP.043: M. Nowacki, M. Pochoda, D. Kacprzak, N. Ogonowska, V. Napolitano, S. Rioton, M. Wróbel, V. Kalel, R. Erdmann, G. Dubin, G. Popowicz, M. Sattler, O. Plettenburg, M. Dawidowski
Structure-based design of new pyrazolo[4,3-c]pyridine as PEX14-PEX5 protein-protein interaction (PPI) inhibitors
PPP.044: P. Mróz, M. Marciniak, R. Fino, V. Napolitano, G. Popowicz, M. Dawidowski
Helical mimetics as novel inhibitors of PEX14-PEX5 protein-protein interaction
PPP.045: K. Lejwoda, A. Gumieniczek, A. Filip, A. Berecka-Rycerz, N. Data
Photostability and phototoxicity of diflunisal and betamethasone
PPP.046: A. Witkowska, E. U. Stolarczyk, A. Groman
Application of GC-MS and LC-MS/MS techniques for direct analysis of amines in pharmaceutical substances
PPP.047: K. Lejwoda, A. Berecka-Rycerz, A. Gumieniczek, H. Trębacz, A. Barzycka, E. Leyk, M. Wesołowski
Chemical stability of linagliptin using HPLC-UV, FT-IR, NIR and DSC methods with chemometric assessment
PPP.048: E. Garbiec, N. Rosiak, J. Cielecka-Piontek, E. Tykarska, P. Zalewski
Lysine as effective amorphous stabilizer for sinapic acid
PPP.049: K. Wdowiak, N. Rosiak, E. Tykarska, J. Cielecka-Piontek
Amorphous dispersion of diosmin and hesperidin
PPP.050: A. Barzowska, B. Pucelik, M. Dawidowski, A. Czarna
Searching for molecular target(s) of AC27 compound
PPP.051: J. Dąbrowska, P. Bilski, E. Kowalska, B. Kubiak
Compatibility between formulation and container in pharmaceutical foam formulation
PPP.052: E. Sługocka, A. Bucki, J. Godyń, I. Góral, M. Kołaczkowski, A. Więckowska
Search for first-in-class multifunctional kinase inhibitors targeting neurodegenerative pathogenesis of Alzheimer’s disease
PPP.053: L. Gurba-Bryśkiewicz, U. Dawid, D. A. Smuga, W. Maruszak, M. Delis, B. Stypik, K. Szymczak, A. Moroz, A. Błocka, M. Mroczkiewicz, K. Dubiel, M. Wieczorek
Implementation of QbD approach to the development of chromatographic method for the determination of complete impurity profile of the CPL409116 innovative substance, dual JAK/ROCK inhibitor
PPP.054: U. Dawid, L. Gurba-Bryśkiewicz, D. Smuga, D. Hołowińska, K. Mulewski, M. Wąsińska-Kałwa, K. Gałązka, M. Mach, K. Wiśniewski
Development and validation of a new chromatographic method for the analysis of metformin-related substances in innovative drug
Saturday, May 28th, 2022, 14:00-15:00
PSP.17: A. Markowska-Radomska, E. Dluska, K. Kosicki
Cancer treatment based on a doxorubicin double emulsion delivery system aided by a mechanism of synthetic lethality
PSP.18: A. Krawczyk-Łebek, M. Dymarska, T. Janeczko, E. Kostrzewa-Susłow
Flavone glycosides with a chlorine atom obtained by biotransformation as potential membrane integrity factors and antimicrobial agents
PSP.19: J. Kutner, M. Malińska, M. Kisiała, S. Sutuła, K. Woźniak
Core Facility for Crystallographic and Biophysical Research to support the development of medicinal products
PSP.20: W. Tabor, P. Krzyżek, U. Nawrot, A. Mucha, Ł. Berlicki, A. Grabowiecka
Ebselen-based inhibitors of urease affect the viability of Cryptococcus neoformans and Helicobacter pylori
PSP.21: B. Szefler, P. Czeleń
Why the diet is so important during chemotherapy for lung cancer? Molecular modeling (and not only) of affinity of some Pt derivatives to B vitamins.
PSP.22: V. Thiruchenthooran, E. Sánchez-López, A. Gliszczyńska
Optimization of Dexibuprofen Loaded Nanostructured Lipid Carriers: Slow Release and Enhanced Anticancer Activity in In Vitro Studies
PSP.23: A. Świerczek, B. Pomierny, E. Wyska
Pharmacokinetic/Pharmacodynamic Modeling of Selective PDE3, PDE4, and PDE7 Inhibitors in a Mouse Model of Autoimmune Hepatitis
PSP.24: E. Gniazdowska, M. Kaza, K. Buś-Kwaśnik, J. Giebułtowicz
Application of liquid chromatography coupled to mass spectrometry for the determination of dutasteride and its major metabolites in human plasma – pharmacokinetic approach and stability
PSP.25: O. Długosz-Grochowska, M. Lipka, D. Lipka
Novel lipid nanoparticles (LNP) as innovative mRNA carriers to various applications in medicine
PSP.26: K. Znajdek, I. Madura, E. Pindelska
New salts of memantine with enhanced properties – synthesis, structure, and physicochemical characteristics
PSP.27: R. Podgórski, M. Sumińska, M. Rachel, M. Fichna, A. Mazur
Glucocorticoids secretion in patients with cystic fibrosis
PSP.28: P. Kasza, P. Szafrański, J. Sączewski, J. Fedorowicz, K. Pociecha, K. Wójcik-Pszczoła, V. Canale, P. Zajdel, M. Cegła
Safirinium- and Fmoc-based alkyne fluorescent probes for “click” labelling of zidovudine and structurally diverse azides
PSP.29: M. Magdycz, M. Kania, J. Lipner, M. Masnyk, Ł. Mucha, S. Piasecka, K. Sidoryk, A. Krause, S. Pikul
A breakthrough therapeutic solution protecting against the development of the post-traumatic and post-stroke epilepsy
PSP.30: E. Pykacz, M. Nowacki, M. Dawidowski
Synthesis of Dibenzo[b,f][1,4]oxazepin-11(10H)-one derivative with potential Trypanocidal activity
PSP.31: P. J. Rudzki, S. Janowska, P. Gałecki, K. Jarus-Dziedzic, D. Rabczenko, A. Segiet, M. Wieczorek
Pharmacokinetics of esketamine inhaled as dry powder in healthy subjects and patients
PSP.32: D. Kucharski, S. Michorowska, J. Chojnacka, G. Nałęcz-Jawecki, J. Giebułtowicz
The effect of environmental concentrations of selected pharmaceuticals on the metabolome of Ostracods
PSP.33: N. Kocot, R. Mastalerz, J. Dulęba, T. Siódmiak, M. Marszałł
Obtaining pure enantiomers of chiral drugs and chiral building blocks with biocatalytic tools
Saturday, May 28th, 2022, 15:00-16:00
PPP.055: V. Canale, S. Chaumont-Dubel, W. Trybała, G. Satała, A. J. Bojarski, P. Koczurkiewicz-Adamczyk, E. Pękala, P. Marin, P. Zajdel. Sustainable synthesis and in vitro biological evaluation of novel inverse agonists at the 5-HT6 receptor-operated Cdk5 signaling pathway
PPP.056: D. Chełminiak-Dudkiewicz, A. Smolarkiewicz-Wyczachowski, K. Mylkie, M. Ziegler-Borowska
Chitosan-based materials with natural active substance for wound healing
PPP.057: K. Wójcik-Pszczoła, K. Pociecha, E. Wyska, M. Szafarz, G. Chłoń-Rzepa, H. Plutecka, P. Koczurkiewicz-Adamczyk, K. Słoczyńska, K. Piska, N. Kocot, E. Pękala
In vitro ADME-Tox profiling and anti-inflammatory activity of 7,8-disubstituted 1,3-dimethyl-7H-purine 2,6-dione-based pan-PDE inhibitors in murine model of allergic asthma
PPP.058: W. Siemiradzka, B. Dolińska, L. Bułaś
Permeation of albumin through human skin depending on its concentration and the substrate used
PPP.059: M. Drop, G. Satała, P. Koczurkiewicz-Adamczyk, S. Chaumont-Dubel, X. Bantreil, W. Pietruś, O. Bento, V. Canale, E. Pękala, A. Bojarski, P. Marin, F. Lamaty, P. Zajdel
targeting agonist-activated state of 5-HT6 receptor by 2-arylpyrrole derivatives: potential application for the treatment of neurodegenerative disorders
PPP.060: L. Bułaś, W. Siemiradzka, O. Filuś, B. Dolińska
Influence of selected ointment bases on benzocaine release and penetration through model membranes
PPP.061: E. Szymańska, M. Wojasiński, T. Ciach, K. Winnicka
The effect of fluctuations in the vaginal pH on tenofovir disproxyl fumarate permeation and release from chitosan/poly(ethylene oxide) nanofiber film
PPP.062: D. Matyszewska
Interactions of antiviral drugs with model lipid envelope of influenza virus.
PPP.063: P. Grygier, K. Pustelny, G. Dubin, A. Czarna
Polypharmacology towards diabetes
PPP.064: I. Domańska, A. Zalewska, A. Plichta, M. Łyczko, K. Cieśla, M. Sobczak
Studies on the influence of ionizing radiation on new, biodegradable drug delivery systems containing paclitaxel
PPP.065: A. Sarna, I. Domańska, I. Madura, E. Pindelska
Synthesis and physicochemical characteristics of three new febuxostat cocrystals
PPP.066: K. Kosicki, A. Markowska-Radomska, E. Speina, E. Dłuska
Effect of multiple-emulsion therapy on genotoxic and oxidative stress induced by doxorubicin and UV radiation in human fibroblasts
PPP.067: A. Ostróżka-Cieślik, B. Dolińska, F. Ryszka
Effect of copper on the function of isolated pig kidneys stored in simple hypothermia
PPP.068: R. Wolińska, K. Frączek, P. Poznański, A. Nawrocka, M. Zalewska, M. Sacharczuk, M. Bujalska-Zadrożny
Anti-inflammatory activity of Cannabis sativa L. extract in experimental atopic dermatitis
PPP.069: M. Borczuch-Kostańska, P. Justyna, E. Pękala, H. Marona, D. Żelaszczyk, A. Gunia-Krzyżak
Novel potential depigmenting agents from the group of cinnamic acid derivatives
PPP.070: J. Krzywik, W. Mozga, P. Pilaszek, E. Maj, A. Nasulewicz-Goldeman, J. Wietrzyk, A. Huczyński
New colchicine derivatives with improved anticancer potency and selectivity
PPP.071: M. Fordymacka, P. Pilaszek, M. Switalska, J. Wietrzyk, R. Blaszczyk
Adenosine Bisphosphonate Analogs as P2Y1 Receptor Antagonists with Antiproliferative Activity
PPP.072: O. M. Demchuk, M. Masłyk, K. Kubiński, K. Górka, M. Janeczko, A. Martyna, M. Kwaśnik, M. Borkowski, A. Boguszewska-Czubara, J. Kowalczuk
Preparation and assessment of new drug carriers based on silver nanoparticles containing hydrogels
PPP.073: M. Janeczko, A. Martyna, A. Kurowska, M. Masłyk, K. Kubiński, O. M. Demchuk
Derivatives of 4-AN as effective antifungal agents
PPP.074: D. Lewoń-Mrozek, E. Maj, J. Rossowska, J. Wietrzyk
The influence of sirtuin 1 (SIRT1) on the anticancer activity of vitamin D in lung cancer cells
PPP.075: B. Kołodziejska, Ł. Pajchel, J. Kolmas
Synthesis and characterization of multifunctional collagen-nanoapatite composite with a potential haemostatic effect
PPP.076: M. Pocięgiel, J. Pijarowska-Kruszyna, A. Jaroń, P. Garnuszek, R. Mikołajczak
Radiosynthesis study of the novel 131I-labelled 1,2,3-dithiazole-based radiopharmaceutical for L-amino acid transporters molecular imaging and therapy
PPP.077: A. Gawor, B. Czarkowska-Pączek, Z. Gajewski, E. Bulska, L. Pączek
Protein expression changes assay as a tool in monitoring the fluorinated drug treatment
PPP.078: E. Bulska, A. Gawor, Z. Gajewski, B. Czarkowska-Pączek, L. Pączek
Fluorination of selected proteins in rats as a result of fluorine-containing drug administration
PPP.079: K. Abramski, B. Mantur, M. Kaza, P. J. Rudzki
Determination of rivaroxaban concentration in human plasma using LC-MS/MS technique
PPP.080: J. Pérez, Ł. Berlicki
De novo foldameric mini-protein as inhibitors of PD-1/PD-L1 interaction
PPP.081: A. Ciesiolkiewicz, Ł. Berlicki
Miniprotein-based PD-1/PD-L1 interaction inhibitors
PPP.082: M. Kaza, D. Włodarczyk, K. Abramski, K. Jarus-Dziedzic, B. Mantur, D. Rabczenko, P. J. Rudzki, A. Segiet, M. Wieczorek
First-in-human pharmacokinetic study of a JAK/ROCK dual inhibitor CPL409116
PPP.083: A. Langer, T. Bartoschik, J. Nowak, N. Kubisa, C. Hatty
Utilizing isothermal spectral shift detection to quantify challenging biomolecular interactions with Monolith X
PPP.084: K. Stępień, J. Giebułtowicz
Tryptophan dietary supplements – release test, targeted and untargeted screening
PPP.085: M. Jędrzejewski, D. Pisklak, Ł. Szeleszczuk
Theoretical insight into Loganic Acid Methyltransferase activity: a combined MD and QM study
PPP.086: B. Milanowski, M. Sosnowska
Dissolution assessment of oral locally acting peptide drug product
PPP.087: P. Kulinowski, P. Malczewski, M. Łaszcz, E. Baran, B. Milanowski, M. Kuprianowicz, P. Dorożyński
3D printing by selective laser sintering and characterization of composite highly drug-loaded floating tablets with insoluble matrix
PPP.088: O. Michalak, P. Krzeczyński, W. Szymanowski, M. Kubiszewski, M. Cybulski, K. Bielawski, A. Bielawska
Synthesis and cytotoxicity of novel ursolic acid derivatives containing an amino acid moiety
PPP.089: C. Suarez, I. Domańska, I. Madura, E. Pindelska
Multicomponent new crystals of erlotinib – structural and pharmaceutical studies
PPP.090: M. Król, K. Baczyński, I. Mames, A. Zarębski, A. Sabiniarz, M. Potocki
DNA Encoded Libraries at Ryvu – preliminary design
PPP.091: A. Żychowska, Ł. Pajchel
Synthesis and physicochemical characterization of an Mesoporous Silica material/Hydroxyapatite/Natural Polymer composite for potential use like drug delivery system
PPP.092: B. Laurence M., N. Lorne, V. Lawrie, M. Basanta-Sanchez, B. Rivera, A. Pietracho
Analytical Characterization of Oligonucleotides by Liquid Chromatography – (LC) High Resolution Mass Spectrometry (HRMS) and State-of-the-Art Analytical Software
PPP.093: R. Eggleston-Rangel, J. Anspach, J. E. Van Eyk, S. Kreimer, A. Ardle, A. Binek, A. Rivas, D. Manalo, C. Phebus, B. Chazarin, A. Moradian, C. Bystrom, A. Pietracho
Development of a Workflow for Deep Proteome Profiling in Human Plasma by Micro-LC-MS/MS
PPP.094: A. Jagusiak, M. Lasota, D. Jankowski
Supramolecular ribbon-like ligands as drug delivery systems for BMS-354825 to bladder cancer cells of T24 line
PPP.095: S. Michorowska, N. Korytowska, R. Piotrowski, J. Giebułtowicz
Deciphering the underlying causes of ineffective therapy with increased rivaroxaban doses using untargeted metabolomics
PPP.096: M. Strózik, M. Strzebońska, K. Skiba, W. Tatara
Development and validation of analytical methods for determination of bromhexine hydrochloride and related impurities in novel orodispersible tablets
PPP.097: A. Kalicka, K. Stępień, J. Giebułtowicz, Z. Fijałek
Use of liquid chromatography associated with mass spectrometry (LC-MS/MS) to determine the composition of illegal pharmaceutical products containing anabolic-androgenic steroids
PPP.098: E. Balcer, J. Giebułtowicz, M. Sochacka, A. Ruszczyńska, M. Muszyńska, E. Bulska
In vitro studies on 4-borono-L-phenylalanine uptake in non-small cell lung cancer and normal lung cells
PPP.099: M. Moratalla, Ł. Pajchel
Synthesis and physicochemical characterization of an SBA-16/HA composite for potential drug delivery
PPP.100: I. Madura, E. Pindelska, M. Mogilnicki, J. Jaśkowska
Structural studies of constitutional isomers of new arylpiperazine ligands for serotonin receptors
PPP.101: K. Pajor, Ł. Pajchel, A. Zgadzaj, J. Kolmas
Synthesis of the modified biphasic calcium phosphate granules with antibacterial properties for potential use in bone repair surgery
PPP.102: M. Artymowicz, W. Struck-Lewicka, D. Siluk, M. Markuszewski, M. Matuszewski, M. J. Markuszewski
Method development and validation for targeted analysis of modified nucleosides and deoxynucleosides in urine samples obtained from patients diagnosed with bladder cancer
PPP.103: P. Koczurkiewicz-Adamczyk, B. Gąsiorkiewicz, A. Mróz, A. Gunia-Krzyżak, K. Piska, B. Władyka, M. Jamrozik, K. Wójcik-Pszczoła, A. Bucki, M. Kołaczkowski, E. Pękala
Cinnamic acid derivatives as chmosensitizers that modulate activity of anthracyclines antibiotic- involvement of CBR1 and AKR1C3 inhibition mechanism
PPP.104: R. Nawrot, J. Gracz-Bernaciak, O. Mazur, N. Kielich, M. Krakowiak, S. Bałdysz, M. Węglewska, O. Musidlak, A. Warowicka, A. Goździcka-Józefiak
Latex of Chelidonium majus – a rich source of potent bioactive compounds
PPP.105: M. Rycerz, P. Poznański, M. Sacharczuk, M. Bujalska-Zadrożny, A. Lesniak
The significance of microglial activation following mild traumatic brain injury (mTBI) in mouse lines selected for high (HA) and low (LA) intensity of depressive-like behaviors
PPP.106: S. Gadowski, K. Tomiczak, Ł. Komsta
Non-negative Principal Component Analysis in TLC Fingerprinting of 21 in-vitro grown Gentiana species
PPP.107: L. Milewski, S. Knippenberg, S. Osella
COX-2 binded fluorescence probe as cancer identification
PPP.108: A. Gurba, P. Szymański, S. Lipiec, I. Agnieszczak, P. Taciak, I. Młynarczuk-Biały, M. Bujalska-Zadrożny, J. Fichna
Innovative Anti-Cancer Therapeutics Based on Gold (III) Complexes in Colorectal Cancer – in vitro studies
PPP.109: M. Jamrozik, K. Piska , A. Bucki, P. Koczurkiewicz-Adamczyk, M. Sapa, M. Kołaczkowski, E. Pękala
Computer-aided design of carbonyl reductase 1 (CRB1) inhibitors as cancer chemosensitizing agents
PPP.110: A. Pogorzelska , , P. Krug, M. Mazur, M. Świtalska, J. Wietrzyk, K. Wiktorska
The enhanced activity of doxorubicin in breast cancer therapy due to sulforaphane properties