Grzegorz Popowicz

Ph.D.; Institute of Structural Biology, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health


Dr. Popowicz’s initial education was Medicinal Physics (MSc). Later, he focused on structural biology in the group of Professor Robert Huber (Nobel Prize in Chemistry 1988) at the Max Planck Institute for Biochemistry, Martinsried. He completed his doctorate in 2006 and continued research as a postdoctoral fellow under supervision of prof. Huber. He used X-ray crystallography, NMR and computational techniques to solve structures and explain function of proteins critical for health and linked to disease. His hallmark works include solving a structure of Insulin-like Growth Factor (IGF) Binding Proteins in complex with IGF and its receptors, the first published structure of MDMX oncoprotein and the development of peptidic and small molecule MDMX inhibitors. In 2012, he joined the Institute of Structural Biology at Helmholtz Zentrum München as a Senior Scientist. He organized a Structure- and Fragment-based Drug Discovery facility that integrated with HMGU drug discovery activities. He later became a group leader with a team focusing on structure-based drug discovery.