Zygmunt Derewenda

PhD, DSc, Professor; University of Virginia School of Medicine, Department of Molecular Physiology and Biological Physics


Dr. Derewenda has been trained as a macromolecular crystallographer and his filed on interest is protein structure and function, and protein-protein and protein-ligand interactions. He co-authored seminal papers about the mechanism of haemoglobin oxygenation and a number of pioneering structure determination of novel enzymes, such as lipases and esterases and select viral proteins He developed a new approach to protein and protein-ligand crystallization, used by many pharmaceutical companies. His current interest is in the molecular regulation of smooth muscle contraction.